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The anatomical distribution of GLP-1R throughout the reproductive system and several preclinical evidence support that GLP-1 can modulate the HPG axis activity at different levels, thus connecting reproductive functions, metabolic system, nutrition, and energy homeostasis mechanisms
If you are in your first month and accidentally take a maintenance-level dose, you have essentially skipped three months of gradual adaptation
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Beyond retatrutide, other pharmaceutical companies are also working on next-gen therapies (including oral pills that mimic these injectables, and even combinations targeting four hormones)
Journal reference: Jensen SBK, Srensen V, Sandsdal RM, et al
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